KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMS1
All Species:
16.97
Human Site:
Y891
Identified Species:
33.94
UniProt:
P54277
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54277
NP_000525.1
932
105830
Y891
L
S
R
Q
L
P
M
Y
L
S
K
E
D
I
Q
Chimpanzee
Pan troglodytes
XP_515987
1061
120272
Y1020
L
S
R
Q
L
P
M
Y
L
S
K
E
D
I
Q
Rhesus Macaque
Macaca mulatta
XP_001103074
831
93641
I800
K
E
D
I
Q
D
I
I
Y
R
M
K
H
Q
F
Dog
Lupus familis
XP_536002
930
105612
Y889
L
S
R
Q
L
P
M
Y
L
S
K
E
D
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
P54279
859
95207
I828
A
S
E
M
K
K
L
I
T
H
M
G
E
M
D
Rat
Rattus norvegicus
NP_001009535
919
103710
Y878
L
S
R
Q
L
P
M
Y
L
P
Q
E
D
V
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507554
871
92244
A836
W
S
S
D
T
S
P
A
W
A
D
V
P
A
G
Chicken
Gallus gallus
NP_001006508
916
103017
H873
L
A
R
Q
L
P
L
H
L
S
K
E
D
V
E
Frog
Xenopus laevis
NP_001079545
925
103654
N881
L
S
R
Q
L
P
L
N
L
S
K
E
D
V
Q
Zebra Danio
Brachydanio rerio
NP_958476
896
98728
S844
L
A
R
Q
L
P
L
S
L
S
R
A
D
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188203
734
80915
F664
R
Q
H
P
T
L
D
F
M
S
I
N
K
I
L
Poplar Tree
Populus trichocarpa
XP_002321013
915
101109
A866
S
S
V
M
I
G
D
A
L
G
R
N
E
M
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.4
86.2
83.6
N.A.
22.3
73.7
N.A.
35.9
58.3
50.7
46.1
N.A.
N.A.
N.A.
N.A.
28.3
Protein Similarity:
100
87.7
87.7
92.6
N.A.
41.6
86
N.A.
50.7
74.6
69
64.6
N.A.
N.A.
N.A.
N.A.
45.8
P-Site Identity:
100
100
0
93.3
N.A.
6.6
80
N.A.
6.6
66.6
80
53.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
13.3
100
N.A.
26.6
93.3
N.A.
13.3
100
93.3
80
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
23.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
45.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
0
0
0
0
0
17
0
9
0
9
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
9
0
9
17
0
0
0
9
0
59
0
9
% D
% Glu:
0
9
9
0
0
0
0
0
0
0
0
50
17
0
9
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% F
% Gly:
0
0
0
0
0
9
0
0
0
9
0
9
0
0
9
% G
% His:
0
0
9
0
0
0
0
9
0
9
0
0
9
0
0
% H
% Ile:
0
0
0
9
9
0
9
17
0
0
9
0
0
25
0
% I
% Lys:
9
0
0
0
9
9
0
0
0
0
42
9
9
0
0
% K
% Leu:
59
0
0
0
59
9
34
0
67
0
0
0
0
0
9
% L
% Met:
0
0
0
17
0
0
34
0
9
0
17
0
0
17
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
0
17
0
0
0
% N
% Pro:
0
0
0
9
0
59
9
0
0
9
0
0
9
0
0
% P
% Gln:
0
9
0
59
9
0
0
0
0
0
9
0
0
9
50
% Q
% Arg:
9
0
59
0
0
0
0
0
0
9
17
0
0
0
0
% R
% Ser:
9
67
9
0
0
9
0
9
0
59
0
0
0
0
0
% S
% Thr:
0
0
0
0
17
0
0
0
9
0
0
0
0
0
9
% T
% Val:
0
0
9
0
0
0
0
0
0
0
0
9
0
42
0
% V
% Trp:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
34
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _